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Data-Driven Simulator for Mechanical Circulatory Support with Domain Adversarial Neural Process

arXiv.org Artificial Intelligence

We propose a data-driven simulator for Mechanical Circulatory Support (MCS) devices, implemented as a probabilistic deep sequence model. Existing mechanical simulators for MCS rely on oversimplifying assumptions and are insensitive to patient-specific behavior, limiting their applicability to real-world treatment scenarios. To address these shortcomings, our model Domain Adversarial Neural Process (DANP) employs a neural process architecture, allowing it to capture the probabilistic relationship between MCS pump levels and aortic pressure measurements with uncertainty. We use domain adversarial training to combine simulation data with real-world observations, resulting in a more realistic and diverse representation of potential outcomes. Empirical results with an improvement of 19% in non-stationary trend prediction establish DANP as an effective tool for clinicians to understand and make informed decisions regarding MCS patient treatment.


ExClaim: Explainable Neural Claim Verification Using Rationalization

arXiv.org Artificial Intelligence

With the advent of deep learning, text generation language models have improved dramatically, with text at a similar level as human-written text. This can lead to rampant misinformation because content can now be created cheaply and distributed quickly. Automated claim verification methods exist to validate claims, but they lack foundational data and often use mainstream news as evidence sources that are strongly biased towards a specific agenda. Current claim verification methods use deep neural network models and complex algorithms for a high classification accuracy but it is at the expense of model explainability. The models are black-boxes and their decision-making process and the steps it took to arrive at a final prediction are obfuscated from the user. We introduce a novel claim verification approach, namely: ExClaim, that attempts to provide an explainable claim verification system with foundational evidence. Inspired by the legal system, ExClaim leverages rationalization to provide a verdict for the claim and justifies the verdict through a natural language explanation (rationale) to describe the model's decision-making process. ExClaim treats the verdict classification task as a question-answer problem and achieves a performance of 0.93 F1 score. It provides subtasks explanations to also justify the intermediate outcomes. Statistical and Explainable AI (XAI) evaluations are conducted to ensure valid and trustworthy outcomes. Ensuring claim verification systems are assured, rational, and explainable is an essential step toward improving Human-AI trust and the accessibility of black-box systems.


Aortic Pressure Forecasting with Deep Sequence Learning

arXiv.org Machine Learning

Mean aortic pressure (MAP) is a major determinant of perfusion in all organs systems. The ability to forecast MAP would enhance the ability of physicians to estimate prognosis of the patient and assist in early detection of hemodynamic instability. However, forecasting MAP is challenging because the blood pressure (BP) time series is noisy and can be highly non-stationary. The aim of this study was to forecast the mean aortic pressure five minutes in advance, using the 25 Hz time series data of previous five minutes as input. We provide a benchmark study of different deep learning models for BP forecasting. We investigate a left ventricular dwelling transvalvular micro-axial device, the Impella, in patients undergoing high-risk percutaneous intervention. The Impella provides hemodynamic support, thus aiding in native heart function recovery. It is also equipped with pressure sensors to capture high frequency MAP measurements at origin, instead of peripherally. Our dataset and the clinical application is novel in the BP forecasting field. We performed a comprehensive study on time series with increasing, decreasing, and stationary trends. The experiments show that recurrent neural networks with Legendre Memory Unit achieve the best performance with an overall forecasting error of 1.8 mmHg.


Binary and Multiclass Classifiers based on Multitaper Spectral Features for Epilepsy Detection

arXiv.org Machine Learning

Epilepsy is one of the most common neurological disorders that can be diagnosed through electroencephalogram (EEG), in which the following epileptic events can be observed: pre-ictal, ictal, post-ictal, and interictal. In this paper, we present a novel method for epilepsy detection into two differentiation contexts: binary and multiclass classification. For feature extraction, a total of 105 measures were extracted from power spectrum, spectrogram, and bispectrogram. For classifier building, eight different machine learning algorithms were used. Our method was applied in a widely used EEG database. As a result, random forest and backpropagation based on multilayer perceptron algorithms reached the highest accuracy for binary (98.75%) and multiclass (96.25%) classification problems, respectively. Subsequently, the statistical tests did not find a model that would achieve a better performance than the other classifiers. In the evaluation based on confusion matrices, it was also not possible to identify a classifier that stands out in relation to other models for EEG classification. Even so, our results are promising and competitive with the findings in the literature.


UPS tests drone delivery to MA island

USATODAY - Tech Top Stories

A UPS drone as it takes a three-mile test flight over open ocean outside of Boston. The test was one of a series of tests to show unmanned aerial vehicles can safely be used for deliveries in the United States. The drone was built by CyPhy, a Danvers, Mass.-based drone and technology company. A UPS drone took a three mile trip over open ocean outside of Salem, Mass. The test was meant to simulate delivery of urgently needed medicine from Beverly, Mass. to Children's Island, which is home to a YMCA day camp.


The Information-Form Data Association Filter

Neural Information Processing Systems

This paper presents a new filter for online data association problems in high-dimensional spaces. The key innovation is a representation of the data association posterior in information form, in which the "proximity" of objects and tracks are expressed by numerical links. Updating these links requires linear time, compared to exponential time required for computing the exact posterior probabilities. The paper derives the algorithm formally and provides comparative results using data obtained by a real-world camera array and by a large-scale sensor network simulation.


The Information-Form Data Association Filter

Neural Information Processing Systems

This paper presents a new filter for online data association problems in high-dimensional spaces. The key innovation is a representation of the data association posterior in information form, in which the "proximity" of objects and tracks are expressed by numerical links. Updating these links requires linear time, compared to exponential time required for computing the exact posterior probabilities. The paper derives the algorithm formally and provides comparative results using data obtained by a real-world camera array and by a large-scale sensor network simulation.


Semi-Supervised Support Vector Machines

Neural Information Processing Systems

We introduce a semi-supervised support vector machine (S3yM) method. Given a training set of labeled data and a working set of unlabeled data, S3YM constructs a support vector machine using both the training and working sets. We use S3 YM to solve the transduction problem using overall risk minimization (ORM) posed by Yapnik. The transduction problem is to estimate the value of a classification function at the given points in the working set. This contrasts with the standard inductive learning problem of estimating the classification function at all possible values and then using the fixed function to deduce the classes of the working set data.


Semi-Supervised Support Vector Machines

Neural Information Processing Systems

We introduce a semi-supervised support vector machine (S3yM) method. Given a training set of labeled data and a working set of unlabeled data, S3YM constructs a support vector machine using both the training and working sets. We use S3 YM to solve the transduction problem using overall risk minimization (ORM) posed by Yapnik. The transduction problem is to estimate the value of a classification function at the given points in the working set. This contrasts with the standard inductive learning problem of estimating the classification function at all possible values and then using the fixed function to deduce the classes of the working set data.